While I did learn that in High-School Biology (Genx here) they don't really teach that in School anymore (at least in the USA they don't). I'm always amazed, when I talk to Millenials or GenY, at what they don't know.

I'm sorry to disagree here, but that's just not true, my friend. The Murican educational system is the best excuse I have ever seen for scientific illiteracy. Critical thinking is drilled out of them from their first day in school, and theocratic indoctrination starts before they can even speak. All too often I come across people with the misguided notion that murica is still a shining city on a hill, when their healthcare, infrastructure, and politics makes it excruciatingly clear that it's just Iran with water.

This is about race. Not gender or age. Everyone knows gender and age makes a difference, but people say 'color' doesn't matter and if you think it does, you're labeled a racist. Turns out, it does matter, at least for things like this (also certain ethnicities are more prone to certain diseases). I understand people don't know this.

I don't know why they are downvoting you you are right.

This is about race. Not blood type. Everyone knows blood type makes a difference, but people say 'color' doesn't matter and if you think it does, you're labeled a racist. Turns out, it does matter, at least for things like this (also certain ethnicities are more prone to certain diseases). I understand people don't know this.

Yes, it's not about race, but about heredity, and someone of the same skin color is more likely to share heredity with someone else of the same skin color, just like a family member is more likely to share traits with another family member. We've known for ages that certain diseases are more prevalent in certain races. That has nothing to do with abilities or intelligence, like some racists like to claim, but the fact that you are are more likely to be somewhat related to someone who is the same color.

I was wondering the same. I have a friend who is Asian/African, her husband is German/Native American/African American, what about their kids? Would like to know.

Tests are performed on the patient first to find out what 'type' they are, depending on what's being tested. They then try to find someone on the registry who's a match.

The answer to this question is "depends". There are so many factors including the disease by which an individual is being affected by that there really is no true simple answer. It could be that the donor match needed for such an individual would have to be someone with exact same multi-ethnic mix or it could be someone of mainly Korean or Croatian decent or maybe just some random person whom is of 100% Slavic decent (if such an individual exists). There really are too many variables to say one way or another.

Each individual with mixed heritage, or however you prefer to phrase it, will have their set of HLA factors. They can vary between siblings. These days, HLA factors tend to be more considered, so if someone from, say, Japan was a best match for your hypothetical child... It just means that's where the HLA factors best matched up for donation. A second child of the same family might find a best donor match in south-central Europe. Since technically Europe and ASsia are a single land mass, subject to migration within, HLA factors in Eurasians are shared where they aren't found in Native American or Pacific or African populations, for example. Quite a lot goes into it, but simply put: Work outward from immeditae family and then look for common heritage. I hope that helped but... If not, I apologize. It's been a while since I did some work on blood types and disease and all that..

For tissue matches, you're in a very bad place. Indeed "first ask family" in general, but in your kids' case ALL family is 50% genetically "other" so there is little point. Especially if you then live in a third country (say, Peru or Mali) then it gets completely hopeless. For different things there's different markers, like the MHC for immunocompatibility (bone marrow donations), where the world population falls in different clusters not necessarily along skin colour lines.