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One Twin Ages Naturally, The Other Gets Botox, And Netizens Compare Both
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One Twin Ages Naturally, The Other Gets Botox, And Netizens Compare Both

Interview With Expert One Twin Ages Naturally, The Other Gets Botox, And Netizens Compare BothViral Twin Study Comparing Botox To Natural Aging Leaves Netizens Unconvinced By Anti-Aging ClaimsPlastic Surgeon Tests Botox For 13 Years On Two Twins, Dividing Opinions: “One Face Can Move”Netizens Question Study Comparing Botoxed Twin To Naturally Aged Sister After Photos Go ViralScientist Challenges Aging, Explaining Botox Study On Identical Twins: Twin Sisters Prove Botox’s Effectiveness In “Groundbreaking” Study: Twin Study Of Botox vs. Natural Aging Sparks Debate: “Beauty Is Defined By So Much More”After Photos Of Botoxed And Naturally Aged Twins Go Viral, Netizens Cast Doubt On The StudyNetizens Cast Doubt On Botox Study As Photos Of Twins Comparing It To Natural Aging Go Viral
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A study on Botox labeled as “groundbreaking” compared the evolution of two identical twins, with one receiving constant injections over 13 years and the other aging as nature intended.

Pictures of the two women, which could easily be mistaken for a miraculous before and after, went viral, with the study’s author triumphantly presenting his results as the ultimate proof of Botox being the definitive anti-aging compound.

Highlights
  • 13-year Botox study on identical twins sparks debate about anti-aging.
  • The treated twin had less forehead and eye wrinkles than untreated one, but netizens were unconvinced
  • Dr. Binder, the study's author, owns stock in the company responsible for the Botox brand
  • Experts warn improper Botox use can cause visual and swallowing issues, but is otherwise an effective anti-aging treatment

The treated twin showed considerably younger skin, with much less noticeable wrinkles on her forehead and around her eyes, which the paper attributed to her receiving up to three doses of the serum for more than a decade.

Netizens, however, were not as impressed, with some dismissing the comparison as the result of factors unrelated to the toxin and others preferring the more natural look of the untreated twin.

“I’m sick of this as being a beauty standard for women,” one reader wrote. “Many of us don’t care about having wrinkles as we age.”

RELATED:

    A study compared the cases of two identical twins, one who had bi-annual Botox injections for 13 years, and the other who didn’t. Netizens are divided over the results

    Image credits: Mary Ann Liebert, Inc.

    The study, published in the Archives of Facial Plastic Surgery, compared the presence of imprinted facial lines in identical twin sisters, one of whom had received botox treatment in the forehead and glabellar region regularly for 13 years—and one who had not.

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    Dr. William J. Binder, the study’s author, presented the results as part of his life-long work with the toxin. The plastic surgeon became known in 1992 for using Botox to alleviate chronic migraines. He discovered that the toxin was not only useful in diminishing muscle tension related to the illness but directly inhibited the release of the neurotransmitters responsible for the pain.

    Image credits: Mary Ann Liebert, Inc.

    Surprised by the toxin’s potential, he embarked on an ambitious project around 1993, contacting the twins that would become the subjects of his research.

    The regularly treated twin received Botox injections approximately 2 to 3 times each year. Conversely, the untreated twin received only two injections in the 13 years the study lasted.

    Image credits: Mary Ann Liebert, Inc.

    The results were impressive, with the treated twin showing a much lesser presence of facial wrinkles, particularly in the forehead and crow’s feet area compared with her sister. The lack of aging did not show on their nasolabial folds, however, as they were left purposely untreated for research purposes.

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    It’s important to note, however, that Dr. Binder is a stockholder and consultant to Allergan Inc., the company responsible for the production of Botox—the famous brand associated with the serum.

    According to experts, improperly applied Botox can seep into organs such as the eyes and throat, causing impaired vision and problems with eating for up to 4 months

    Image credits: Mary Ann Liebert, Inc.

    While Dr. Binder reported “no adverse events during 13 years of regular treatment,” members of the plastic surgeon community have warned against the adverse effects of Botox when administered either improperly or in excess.

    Image credits: Mary Ann Liebert, Inc.

    Bored Panda spoke with Camila Atal, a cosmetic and dental surgeon specializing in Botox injections, who emphasized the importance of going to a licensed professional to ensure proper technique.

    “There’s always the risk of eyelid ptosis: a condition where the eyelid droops and is unable to open or close,” Atal said, explaining how an improperly administered injection can cause the serum to spread to nearby muscles not targeted for treatment, causing them to become lax.

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    Image credits: Mary Ann Liebert, Inc.

    “When this happens, we can try to diminish the effects of the toxin with infrared lasers, but total recovery only occurs once the compound leaves the body in 3 to 4 months.”

    Other reported effects are dysphonia, dysphagia, and dystonia, which can cause the patient to lose the ability to speak and swallow and cause muscle spasms that can last for weeks on end.

    Image credits: Mary Ann Liebert, Inc.

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    “In the hands of a skilled injector who understands the anatomy of the area, adheres to proper dilution guidelines, and respects safety margins, Botox will continue to be an excellent anti-aging treatment,” Atal said, emphasizing the importance of regular check-ups to ensure the patient’s well-being.

    The FDA issued a warning this year after detecting the distribution of counterfeit Botox in the United States, leading to patients being hospitalized

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    Image credits: Anna Shvets/Pexels (Not the actual photo)

    The risks associated with Botox injections have done nothing but increase alongside their popularity.

    The numerous benefits of the serum, which include “helping prevent wrinkles from deepening, softening expression lines, and improving the skin’s texture,” according to specialists like Atal, have led to an increase in demand for cheaper, less “legal,” alternatives.

    Image credits: American Society for Dermatologic Surgery

    In May, the Food & Drug Administration (FDA) issued a warning for consumers and healthcare professionals, after finding unsafe, counterfeit versions of the toxin in multiple states being administered to users seeking cheaper alternatives.

    Image credits: American Society for Dermatologic Surgery

    The “FDA is aware of adverse events, including hospitalizations, linked to the counterfeit Botox,” the statement read. 

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    “Symptoms included blurred or double vision, difficulty swallowing, dry mouth, constipation, incontinence, shortness of breath, weakness and difficulty lifting one’s head following injection of these products.”

    Image credits: American Society for Dermatologic Surgery

    According to data released by the American Society of Plastic Surgeons, Botox injections have experienced an astounding increase of 459% from 2000 to 2020, and the numbers show no sign of slowing down, experiencing an annual increase of 5% to 7%.

    The report, interestingly, linked the rise to the boom of weight loss medications like Ozempic, as the rapid weight loss caused by such medications results in a decline in skin elasticity.

    Netizens reacted with skepticism at the results of Dr. Binder’s research, with many attributing the differences to factors unrelated to Botox

    Image credits: American Society for Dermatologic Surgery

    “As a retired facial plastic surgeon, the photos are not equivalent. The twin that received botox are ALL brighter, thus hiding any fine facial wrinkles,” wrote one reader, dismissing the study.

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    “The multitude of variables involved makes it highly improbable that both individuals experienced identical outcomes unless they shared the same exposure to sunlight, stress levels, etc.” another wrote.

    Others expressed concern over the usage of the toxin for such a long period.

    “I find it hard to believe that injecting botulism toxin regularly won’t have other serious side-effects. You might look slightly better, but there ain’t no such thing as a free lunch,” a user argued.

    “Simon Cowell, Amanda Holden, and Patsy Kensit regularly had botox I believe, and although they looked different with it I wouldn’t say they look youthful,” wrote another.

    “Beauty is defined by so much more.”

    “They both look beautiful,” wrote one netizen, echoing the sentiments of many who felt the differences were too small to notice

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    Abel Musa Miño

    Abel Musa Miño

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    Abel is a journalist at Bored Panda. Born in Santiago, Chile, he holds a Bachelor's degree in Communication and a diploma in International Relations. In his spare time, you can find him tinkering with his motorbike, playing with his dog, or reading a good novel.

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    Abel Musa Miño

    Abel Musa Miño

    Writer, BoredPanda staff

    Abel is a journalist at Bored Panda. Born in Santiago, Chile, he holds a Bachelor's degree in Communication and a diploma in International Relations. In his spare time, you can find him tinkering with his motorbike, playing with his dog, or reading a good novel.

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    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    You can call ‘em “marionette lines” if you like, as that’s the colloquial expression for ‘em. Unsure what you’re objecting to unless it’s the “labia” part, but that merely refers to “lips” and obviously, we’re talking about the lines between the nose (“naso-“) and lips (“-labia”). Me, I like to celebrate all KINDSA lips any chance I get, as labia RULE!! 😀

    Load More Replies...
    SpiderWoman13
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    BOTOX is not a "serum"; it is a TOXIN. So, one twin had 'regular Botox"; the other had NO skin treatment - i.e. creams, massage, facials, oils - for years? What sort of nonsense is that? The Botox BARELY makes a difference and arguably, results would have been far closer had the other twin a decent skin regimen/internal nutrition. The risks of Botox DO NOT outweigh the "benefits".

    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    “Serum” and “toxin” aren’t mutually exclusive, and that’s beside the point, but it seems you believe “serum” refers here to something you apply to your skin. It has another meaning, and it’s the other meaning which is used here.

    Load More Replies...
    Roni Stone
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    The only problem I have with any of it is our absolute panic over showing our age. Making sure your skin is healthy is one thing - fearing the inevitable aging process is entirely another, imo. I may be in the minority here, but I embrace my age, my gray hair, my wrinkles and scars - all the rusty parts of my body. It tells my story, my history, and it doesn't pretend that it has all been pretty.

    Karl der Große
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Definitely people look shinier with Botox. You can tell their faces are less expressive, even from these still photos. Watching Meet the Press has really started to creep me out with all the robotic faces.

    FreeTheUnicorn
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Fewer wrinkles but you never look happy, even without the stupid medical risks, it's a bad trade.

    Binky Melnik
    Community Member
    2 days ago (edited) DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    I get Botox for my migraines, and it works *amazingly*, as I can LIVE now! However (and it’s a BIG “however”), in order to use it for such, it needs to be injected into the forehead and the point between the eyebrows. As I knew nothing of it, my first treatment hit all the required areas. About a month later, a neighbor died, and when his body was being wheeled out, I said, “Poor Mr Solomon; he was so sweet!” Several neighbors looked at me angrily and I was baffled when I heard someone say “B***h be pretending she’s all sad, but her face say she don’t give a 💩.” I asked someone I trusted what that was about, and she told me I sure didn’t LOOK sad. Getting a clue, I ran to the mirror and started making faces, and discovered that nothing above my lower eyelids moved … at all. Worse, my lifelong-hooded eyes were now barely visible under the skin, and the skin hung even lower! Now I ask that just half the interbrow n’éjections be done, and to do as little as possible to my forehead. It doesn’t work nearly as well,

    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    but I need my face to FUNCTION! It took about seven months to wear off, and I live almost like a hermit so it wasn’t too, *too* terrible, but when I needed to express emotions (over a death, a birth, a wedding, a jackpot, etc) I did it over the phone because I didn’t wanna hurt people by not displaying the proper emotions on my face. (It was also after the Botox started that suddenly, my lifelong hooded eyes went away and now I have prominent eyelids! Great! I’m now too old for anything but neutral matte eyeshadow so can’t take full advantage of it, dammit, but still, I’m delighted to FINALLY have lids! My eyes FINALLY can make “come hither” looks if I want ‘em to!)

    Load More Replies...
    Traveling Lady Railfan
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Identical twin studies are always fascinating, and I'm going to be honest, 13 years of Botox toxin injections versus untreated natural aging, I saw extremely little difference between the two ladies, except that one looked a little more fake than the other like when they were smiling, one of them you could see the smile around the eyes and the other one looked like she didn't really like you because she couldn't smile because the bacterial toxins have paralyzed the nerve endings and that's why she doesn't have the wrinkles. Yeah. I don't really see the benefit here. They're both beautiful.

    Carole G.
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    After paying the piper for 13 years, not much difference except has a pocket full of cash! Character lines are honest, well deserved honesty.

    Mari
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Almost no result after 13years of botox treatments? I don't understand why people worry about wrinkles. It is ridiculous.

    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    You can call ‘em “marionette lines” if you like, as that’s the colloquial expression for ‘em. Unsure what you’re objecting to unless it’s the “labia” part, but that merely refers to “lips” and obviously, we’re talking about the lines between the nose (“naso-“) and lips (“-labia”). Me, I like to celebrate all KINDSA lips any chance I get, as labia RULE!! 😀

    Load More Replies...
    SpiderWoman13
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    BOTOX is not a "serum"; it is a TOXIN. So, one twin had 'regular Botox"; the other had NO skin treatment - i.e. creams, massage, facials, oils - for years? What sort of nonsense is that? The Botox BARELY makes a difference and arguably, results would have been far closer had the other twin a decent skin regimen/internal nutrition. The risks of Botox DO NOT outweigh the "benefits".

    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    “Serum” and “toxin” aren’t mutually exclusive, and that’s beside the point, but it seems you believe “serum” refers here to something you apply to your skin. It has another meaning, and it’s the other meaning which is used here.

    Load More Replies...
    Roni Stone
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    The only problem I have with any of it is our absolute panic over showing our age. Making sure your skin is healthy is one thing - fearing the inevitable aging process is entirely another, imo. I may be in the minority here, but I embrace my age, my gray hair, my wrinkles and scars - all the rusty parts of my body. It tells my story, my history, and it doesn't pretend that it has all been pretty.

    Karl der Große
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Definitely people look shinier with Botox. You can tell their faces are less expressive, even from these still photos. Watching Meet the Press has really started to creep me out with all the robotic faces.

    FreeTheUnicorn
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Fewer wrinkles but you never look happy, even without the stupid medical risks, it's a bad trade.

    Binky Melnik
    Community Member
    2 days ago (edited) DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    I get Botox for my migraines, and it works *amazingly*, as I can LIVE now! However (and it’s a BIG “however”), in order to use it for such, it needs to be injected into the forehead and the point between the eyebrows. As I knew nothing of it, my first treatment hit all the required areas. About a month later, a neighbor died, and when his body was being wheeled out, I said, “Poor Mr Solomon; he was so sweet!” Several neighbors looked at me angrily and I was baffled when I heard someone say “B***h be pretending she’s all sad, but her face say she don’t give a 💩.” I asked someone I trusted what that was about, and she told me I sure didn’t LOOK sad. Getting a clue, I ran to the mirror and started making faces, and discovered that nothing above my lower eyelids moved … at all. Worse, my lifelong-hooded eyes were now barely visible under the skin, and the skin hung even lower! Now I ask that just half the interbrow n’éjections be done, and to do as little as possible to my forehead. It doesn’t work nearly as well,

    Binky Melnik
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    but I need my face to FUNCTION! It took about seven months to wear off, and I live almost like a hermit so it wasn’t too, *too* terrible, but when I needed to express emotions (over a death, a birth, a wedding, a jackpot, etc) I did it over the phone because I didn’t wanna hurt people by not displaying the proper emotions on my face. (It was also after the Botox started that suddenly, my lifelong hooded eyes went away and now I have prominent eyelids! Great! I’m now too old for anything but neutral matte eyeshadow so can’t take full advantage of it, dammit, but still, I’m delighted to FINALLY have lids! My eyes FINALLY can make “come hither” looks if I want ‘em to!)

    Load More Replies...
    Traveling Lady Railfan
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Identical twin studies are always fascinating, and I'm going to be honest, 13 years of Botox toxin injections versus untreated natural aging, I saw extremely little difference between the two ladies, except that one looked a little more fake than the other like when they were smiling, one of them you could see the smile around the eyes and the other one looked like she didn't really like you because she couldn't smile because the bacterial toxins have paralyzed the nerve endings and that's why she doesn't have the wrinkles. Yeah. I don't really see the benefit here. They're both beautiful.

    Carole G.
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    After paying the piper for 13 years, not much difference except has a pocket full of cash! Character lines are honest, well deserved honesty.

    Mari
    Community Member
    2 days ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

    Almost no result after 13years of botox treatments? I don't understand why people worry about wrinkles. It is ridiculous.

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