The "Perry Bible Fellowship" originated as a self-syndicated webcomic and gained popularity for its dark humor and distinctive art style. Gurewitch began creating comics for his college's student newspaper after a short stint trying to be a journalist for the same paper. The artist told Bored Panda that his motivation is to make people see things in a new way. He has a fascination with sharing confusion, as he believes it sparks wonder and curiosity in people's minds.

PBF is known for its edgy and morbid humor, which has led to controversy and discussions over the years. The comics often explore dark and unconventional themes, and their content may not be suitable for all audiences. While some appreciate its unique and daring approach to humor, others may find it offensive or controversial.

According to Gurewitch, it's interesting how the intended meaning or personality in a creative work can sometimes be misunderstood, but people have the right to interpret it in their own way. But he finds it funny that many perceive a comic as just being provocative without much thought behind it. The artist personally finds it amusing because, when he enjoys his own comics, he can see reflections of his thoughts, things on his mind, or discussions with friends.

The artist shared that usually, ideas for comics come from a random doodle or stroke on a sketchpad. Other times, friends might share ideas. "Sometimes an old sketch will present itself with new opportunities much later on."