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Is The Curious Case Of Benjamin Button actually a documentary? Maybe, if you take a closer look at this new viral challenge. People on TikTok are trying to show that the movie about Brad Pitt getting younger (and hotter) from birth to death is actually about them.

It all started when user @kactavish shared a video of just how much she transformed from when she was a tween to now. Looking at the way she looked at 12 years old vs. 24 years old, other folks started sharing evidence of "aging backward" too. Continue scrolling and take a look at some of the most memorable comparisons.

#1

14 Years Old And 22 Years Old

14 Years Old And 22 Years Old

em_uggghhh Report

The idea of someone "aging backward" seems like an innocent joke, but a small clinical study in California has suggested there might be more to it. Turns out, it might be possible to reverse the body's epigenetic clock, which measures a person's biological age. At least to some extent.

For one year, nine healthy volunteers took a cocktail of three common drugs — growth hormone and two diabetes medications — and on average lost 2.5 years of their biological ages, measured by analyzing marks on a person's genomes. If that wasn't enough, their immune systems also showed signs of rejuvenation.

#2

12 Years Old And 24 Years Old

12 Years Old And 24 Years Old

kactavish Report

The results were a surprise even to researchers. However, they do point out that the findings are preliminary because the trial was small and did not include a control group.

"I'd expected to see slowing down of the clock, but not a reversal," Steve Horvath, a geneticist at the University of California, Los Angeles, who conducted the epigenetic analysis, told Nature. "That felt kind of futuristic."

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#3

13 Years Old And 22 Years Old

13 Years Old And 22 Years Old

_lilgen Report

The trial was carried out mainly to test whether growth hormone could be used safely in humans to restore tissue in the thymus gland, which is located in the chest between the lungs and the breastbone, and is crucial for efficient immune function. White blood cells are produced in the bone marrow and then mature inside the thymus, where they become specialized T cells that help the body to fight infections and cancers. The gland, however, starts to shrink after puberty and increasingly becomes clogged with fat.

#4

14 Years Old And 22 Years Old

14 Years Old And 22 Years Old

bunnymund Report

9 white men between 51 and 65 years of age participated in The Thymus Regeneration, Immunorestoration, and Insulin Mitigation (TRIIM) trial. It was led by immunologist Gregory Fahy, the chief scientific officer and co-founder of Intervene Immune in Los Angeles, and was approved by the US Food and Drug Administration back in May 2015.

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Blood samples showed that the blood-cell count was rejuvenated in each of the participants. The researchers also used magnetic resonance imaging (MRI) to determine the composition of the thymus at the start and end of the study. In seven participants, accumulated fat had been replaced with regenerated thymus tissue.

#5

14 Years Old And 23 Years Old

14 Years Old And 23 Years Old

tmenelas Report

Horvath used four different epigenetic clocks to assess each patient’s biological age. He found significant reversal for each trial participant in all of the tests.

“This told me that the biological effect of the treatment was robust,” he said. Moreover, the effect persisted in the six participants who provided a final blood sample six months after stopping the trial too.

Regenerating the thymus could be useful in people who have underactive immune systems, including older people.

Consider yourself Benjamin Buttoned.

#6

19- Or 20-Ish Years Old And 27 Years Old

19- Or 20-Ish Years Old And 27 Years Old

emerz_ Report

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Eglė Bukauskaitė
Community Member
3 years ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

This one' seasy. 1st photo - dressed like a granny; 2nd like a 5year old (or Baby Spice?)

Diane Aguilar
Community Member
2 years ago DotsCreated by potrace 1.15, written by Peter Selinger 2001-2017

Wow, this is one of the more dramatic transformations on this list. When this person was 19 - 20 she looked like she would be the parent of a 19 - 20 year old, whereas as a 27-year-old she looks like she just graduated from uni. I'm so glad she went with a better hairstyle, clothing, and jewelry options for her age and that she 's let more of her natural appearance shine through with whatever makeup she's got on and hope she continues doing what she does from here on out.

Julius Martin
Community Member
3 years ago

This comment is hidden. Click here to view.

this is bull thats either not her or shes younger in pic 2

Martha Meyer
Community Member
3 years ago

This comment is hidden. Click here to view.

Are people allowed to be on TikTok at age 27? I feel that would make you some sort of wise old Yoda playing with the toddlers in a sand box.

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#7

12 Years Old And Now

12 Years Old And Now

auntkenzie Report

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#8

14 Years Old And 27 Years Old

14 Years Old And 27 Years Old

kategraham2 Report

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#9

14 Years Old An 22 Years Old

14 Years Old An 22 Years Old

anasofia.cesena Report

#10

15 Years Old And 26 Years Old

15 Years Old And 26 Years Old

tayymylottt Report

#11

14 Years Old And 24 Years Old

14 Years Old And 24 Years Old

thatfakelesbian Report

#12

13- Or 14-Ish Years Old And Now

13- Or 14-Ish Years Old And Now

lmao_lame Report

#13

12 Years Old And 22 Years Old

12 Years Old And 22 Years Old

acaciasucks Report

#14

13 Years Old And 18 Years Old

13 Years Old And 18 Years Old

maddiesegar Report

#15

13 Years Old And 24 Years Old

13 Years Old And 24 Years Old

trashbuns Report

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#16

18 Years Old vs. 26 Years Old

18 Years Old vs. 26 Years Old

dragonjpg Report

#17

14 Years Old And 25 Years Old

14 Years Old And 25 Years Old

simplystephjaye Report

#18

12 Years Old And 19 Years Old

12 Years Old And 19 Years Old

ta1king.trash Report

#19

12 Years Old 22 Years Old

12 Years Old 22 Years Old

mack.and.peas Report

#20

13 Years Old And 20 Years Old

13 Years Old And 20 Years Old

gorque Report

#21

18 Years Old And 24 Years Old

18 Years Old And 24 Years Old

jessrobz Report

#22

13 Years Old And 21 Years Old

13 Years Old And 21 Years Old

squidvog Report

#23

13/14 Years Old And 20 Years Old

13/14 Years Old And 20 Years Old

slurpiemcqueen Report

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